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Vaccine Design:
To develop Epitope Based Vaccines through the identification of neutralizing epitopes, molecular characterization of the antibody:epitope interface, reconstitution of the essential conformational discontiuous elements of the epitopes and their use as immunogens to elicit focused and targeted B-cell responses.
High Throughput Diagnostics:
As we learn the details of the antibody response towards specific viruses we implement arrays of meaningful antigenic markers to measure the antibody response towards pathogens in polyclonal sera. This will not only generate potent and sensitive combinatorial diagnostics but produce a new multiplex approach for blood donation screening.
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